Services

The Research Histology Laboratory provides an extensive array of routine and specialized histological services, as well as immunohistochemical stains. The laboratory boasts highly skilled and quality technical and professional pathology services and is capable of assisting researchers at WMed and beyond. Take a look at the laboratory’s full list of services:

Routine Histology

Tissue trimming, processing, embedding, sectioning and staining for routine and research samples.

  • Paraffin and frozen sectioning and staining
  • Bone decalcification and sectioning
  • Unstained slides, serial and step sectioning
  • Conventional staining
  • Barcode labeling of cassettes and slides

Specialty Histology Staining

Histochemical techniques to demonstrate various tissue components.

  • Gram stain
  • GMS
  • Periodic acid Schiff (PAS)
  • Mucicarmine
  • Prussian blue
  • Masson’s trichrome
  • Reticulin
  • Bielschowsky
  • Fontana-Masson
  • Elastin
  • Oil Red O
  • AFB
  • Amyloid

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Immunohistochemistry

Immunohistochemistry for both routine and novel markers.

  • Amyloid-beta
  • Tau AT8
  • Alpha-synuclein
  • TDP-43
  • Neurofilament
  • CD68
  • CD20
  • CD3
  • GFAP
  • Amyloid precursor protein (APP)

Specialty Services

  • Neuropathology – Large brain sectioning
  • Cell block processing
  • Image analysis

Additional stains, antibodies, or custom requests are welcome. For more information, please contact Kristi Bailey, BS, HTL, Lead Histotechnologist at kristi.bailey@med.wmich.edu, or Rudolph J. Castellani, MD, Director, Center for Neuropathology and Research Histology Laboratory, at rudolph.castellani@med.wmich.edu.

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